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Brand new series: More 4 presents the UK premiere of the series that secured Kelsey Grammer his first Golden Globe Award. Grammer plays Chicago Mayor Tom Kane, sitting like a spider at the centre of the city's web of power; a web built on a covenant with the people. They want to be led, they want disputes settled, jobs dispensed, and loyalties rewarded. If Kane achieves these ends through deception and dubious morality, so be it. As long as he gets the job done, they look the other way. He's the most effective mayor in recent history, but a degenerative brain disorder is ripping everything away from him. He can't trust his memory, his closest allies, or even himself. Kane's wife Meredith (Connie Nielsen) knows nothing - theirs is a marriage of convenience. Kitty O'Neil (Kathleen Robertson), Kane's advisor, has her suspicions but stays silent. And Kane's political advisor Ezra Stone (Martin Donovan), a Yale graduate with a rough edge, plays his part without asking questions. Only Emma (Hannah Ware), Kane's estranged daughter, has a chance of learning his secret. This is going to be the toughest term yet for the Boss... This opening episode of the series is directed by Gus Van Sant, one of the show's producers.